Resveratrol supplementation and mitochondrial capacity with exercise in young adults
Polley, Kristine Rose
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PURPOSE: To determine the effects of a 28 day resveratrol supplementation period in combination with a submaximal exercise protocol on skeletal muscle mitochondrial capacity. METHODS: Sixteen healthy young adults were randomly assigned in a double blind fashion into two groups. One group received supplementation of 500 mg of resveratrol and 10 mg of piperine to take daily, while the other group received two placebo pills daily. Supplementation lasted 4 weeks and included 3 sessions per week of low intensity forearm endurance training. Changes in skeletal muscle mitochondrial capacity in the forearm muscle were measured using near-infrared spectroscopy (NIRS). RESULTS: A significant increase (p < 0.05) in mitochondrial capacity occurred at post-testing in the resveratrol group (~40%). The placebo group did not have a significant increase in mitochondrial capacity after 4 weeks of forearm endurance training. CONCLUSION: Resveratrol significantly increased mitochondrial capacity in a submaximal endurance training protocol, where the placebo group had no effect.