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    Efficacy of weekly docetaxel in locally advanced cardiac angiosarcoma

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    13104_2015_Article_1296.pdf (935.4Kb)
    Date
    2015-07-30
    Author
    Minichillo, Santino
    Pantaleo, Maria A
    Nannini, Margherita
    Coccolo, Fabio
    Gatto, Lidia
    Biasco, Guido
    Brandi, Giovanni
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    Abstract
    Abstract Background Primary cardiac angiosarcoma is extremely aggressive; however, it is often misdiagnosed because of its rarity. For locally advanced tumors, doxorubicin-based chemotherapy regimens are the standard of treatment, even if the gain in term of progression-free survival is limited and is no longer than 5 months. Case presentation We report the case of a Caucasian 23-year-old man with locally advanced cardiac angiosarcoma who underwent radical surgical resection after a prolonged response to weekly docetaxel and complementary radiotherapy. Conclusion Combined treatment with weekly docetaxel and radiotherapy may be a valid alternative for the treatment of locally advanced cardiac angiosarcoma; the combination can lead to radical surgical resections, avoiding the cumulative cardiotoxicity of antracycline-based regimens.
    URI
    http://dx.doi.org/10.1186/s13104-015-1296-4
    http://hdl.handle.net/10724/31630
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