Show simple item record

dc.contributor.authorWard, Christie Lynn
dc.description.abstractDeterminants of feelings of energy and physical function in middle-aged women are not well characterized. In addition, middle-aged breast cancer survivors (BCS) may have compromised feelings of energy and function due to the effects of disease and treatment. This study aimed to: 1) determine the contributions of adiposity and physical activity (PA) to feelings of energy in middle-aged postmenopausal women (N=74), 2) examine associations among PA, adiposity, and muscle quality (MQ) and physical function (N=64), and 3) determine if BCS differ from age and adiposity matched controls (CON) (N=13 per group) in feelings of energy and physical function. Body composition was measured via dual energy x-ray absorptiometry, PA via hybrid pedometer [steps∙day-1, daily moderate to vigorous PA (MVPA)], vitality with the SF-36, leg strength and power via isokinetic dynamometry [60°∙sec-1, (KN60)], and power rig. MQ was calculated as the ratio of: 1) KN60 to upper leg lean mass (MQ-KN60), and 2) power to lower body lean mass (MQ-Power). Physical function was evaluated with timed up and go (UPGO), 30-sec chair stand (CHR), and 6-minute walk (WALK). MVPA independently explained 8% of variance in vitality. Age and MQ-KN60 were independently related to CHR. Age and MQ-Power were significantly associated with UPGO. Total medical conditions, MQ-KN60, steps∙day-1, and adiposity were predictors of WALK. Fatigue, energy, and PA were similar in BCS and CON; however, CON performed better than BCS on UPGO (15.8%, p=.05). In BCS and CON, group was a significant predictor of UPGO, group and MQ-KN60 were related to CHR, and adiposity explained 12% of WALK variance; however, when substituting MQ-Power into the regression analyses, steps∙day-1 were related to UPGO and CHR, while adiposity explained 10% of WALK. Middle-aged women, including BCS, should engage in recommended amounts of PA to preserve feelings of energy, regardless of weight status, and maintain MQ for better physical function.
dc.subjectphysical function
dc.subjectbody composition
dc.subjectphysical activity
dc.subjectmuscle quality
dc.subjectpostmenopausal women
dc.subjectbreast cancer survivors
dc.titleFatigue and physical function in postmenopausal women, including breast cancer survivors
dc.title.alternativeexploring the contributions of body composition, physical activity and muscular performance
dc.description.advisorEllen Evans
dc.description.committeeEllen Evans
dc.description.committeeLaura Rogers
dc.description.committeePatrick J O'Connor
dc.description.committeeMary Ann Johnson

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record