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dc.contributor.authorFoss, Stephanie
dc.description.abstractVitamin D may play a role in muscle function. The effects of changes in serum vitamin D on myokines in 64 male and female, black and white adolescents (9-13 years) was determined following 12 weeks of vitamin D supplementation. Serum 25-hydroxyvitamin D {25(OH)D}, 1,25-dihydroxyvitamin D {1,25(OH)2D}, myostatin, follistatin, and insulin-like growth factor 1 (IGF-I)] were measured at baseline and 12 weeks. At baseline, black males had significantly higher myostatin concentrations than white males. Concentrations of 25(OH)D and 1,25(OH)2D increased significantly over 12 weeks, while myostatin, follistatin, and IGF-I did not change. This data suggests that large changes in serum 25(OH)D over 12 weeks does not alter myokines, but the differences in myostatin concentrations by race warrants further investigation.
dc.subjectVitamin D, Adolescents, Supplementation, Myostatin, Follistatin, IGF-I
dc.titleVitamin D supplementation and myokine response in early pubertal adolescents
dc.description.departmentFoods and Nutrition
dc.description.majorFoods and Nutrition
dc.description.advisorRichard Lewis
dc.description.committeeRichard Lewis
dc.description.committeeEmma Laing
dc.description.committeeDorothy Hausman

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