Functional activation during the stroop task in normal older adults & MCI
Puente, Antonio Nicolas
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The purpose of this study was to compare the neural activation of inhibition with functional Magnetic Resonance Imaging (fMRI) between normal and older adults with mild cognitive impairment (MCI). It was hypothesized that individuals with MCI have greater activation in specific brain regions. This hypothesis was not supported given there was no difference between groups in hypothesized regions or in post-hoc whole brain analyses with corrected thresholds. However, several measures from a neuropsychological battery were able to differentiate between normal and older adults with MCI. Results suggest traditional neuropsychological techniques may be superior to fMRI in detecting MCI.