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dc.contributor.authorSherlock, Ceri Elinor
dc.date.accessioned2014-03-04T20:22:35Z
dc.date.available2014-03-04T20:22:35Z
dc.date.issued2011-08
dc.identifier.othersherlock_ceri_e_201108_ms
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/sherlock_ceri_e_201108_ms
dc.identifier.urihttp://hdl.handle.net/10724/27592
dc.description.abstractLaminitis is a painful, debilitating and life-threatening disease affecting horses worldwide. The disease can arise after local or systemic insults and the pathogenesis is not well understood. Alterations in laminar blood flow have been implicated in the pathogenesis of laminitis; however, controversy exists regarding the nature of these changes. The purposes of this study were to develop and evaluate a new technique for measuring laminar blood flow in horses. Using a technique to measure cerebral blood flow in humans, xenon133 in solution was injected intra-arterially in the metacarpal region of healthy horses and the gamma radiation emitted at the dorsal laminae was recorded. The results of this study indicate that xenon¹³³ solution can be safely injected intra-arterially in healthy horses, and that similar peaks in gamma radiation are recorded at the hoof wall. Consequently, this technique may provide useful information about alterations in laminar blood flow in horses with laminitis.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subjectXenon133
dc.subjectHorse
dc.subjectLaminitis
dc.subjectLaminar blood flow
dc.titleEvaluation of xenon133 washout for measurement of laminar blood flow in the horse
dc.typeThesis
dc.description.degreeMS
dc.description.departmentVeterinary and Biomedical Sciences
dc.description.majorVeterinary and Biomedical Sciences
dc.description.advisorJohn Peroni
dc.description.committeeJohn Peroni
dc.description.committeeTom Robertson
dc.description.committeeJames Moore


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