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dc.contributor.authorAppleby, Lauren Mary
dc.date.accessioned2014-03-04T18:55:05Z
dc.date.available2014-03-04T18:55:05Z
dc.date.issued2010-08
dc.identifier.otherappleby_lauren_m_201008_ms
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/appleby_lauren_m_201008_ms
dc.identifier.urihttp://hdl.handle.net/10724/26558
dc.description.abstractThe control of avian influenza is most effectively approached from multiple angles. In this research, two aspects of the management of this disease were examined. The first objective was to establish a species-independent competitive ELISA for the detection of antibodies against hemagglutinin 6 (H6). Characterization of the monoclonal antibodies (mAbs) developed toward this purpose revealed that all four mAbs were specific for linear epitopes within the esterase domain of H6. One of the mAbs was also found to be neutralizing. Another aim of the research was to evaluate the efficacy of metam-sodium as a disinfectant of poultry litter. The removal of pathogens which persist in litter is required for its safe disposal, yet few agents are able to effectively penetrate this porous material. It was found that the manufacturer’s recommended concentration was able to completely eliminate infectious avian influenza virus and infectious bursal disease virus from contaminated poultry litter.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subjectavian influenza virus
dc.subjecthemagglutinin
dc.subjectH6, monoclonal antibody
dc.subjectcompetitive ELISA
dc.subjectmetam-sodium
dc.subjectinfectious bursal disease virus
dc.subjectdisinfectant
dc.subjectlitter
dc.titleDevelopment of methods for the detection and control of low-pathogenic avian influenza virus
dc.typeThesis
dc.description.degreeMS
dc.description.departmentPopulation Health
dc.description.majorVeterinary and Biomedical Sciences
dc.description.advisorEgbert Mundt
dc.description.committeeEgbert Mundt
dc.description.committeeHolly Sellers
dc.description.committeeMaricarmen Garcia


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