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dc.contributor.authorHwang, Jenny Ying-Chieh
dc.date.accessioned2014-03-04T18:19:13Z
dc.date.available2014-03-04T18:19:13Z
dc.date.issued2009-08
dc.identifier.otherhwang_jenny_y_200908_ms
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/hwang_jenny_y_200908_ms
dc.identifier.urihttp://hdl.handle.net/10724/25825
dc.description.abstractThe present study determined the effects of the lethal acrodermatitis (LAD) mutation, dietary zinc deficiency, and exercise on the protein composition of lipid rafts. The lipid rafts from LAD dog kidney and rat liver were separated using the ice-cold Triton X-100. Two dimensional gel electrophoresis (2DE) was utilized for identifying differential protein expression in these membrane fractions. Rats were fed diets containing 5 and 30 ppm zinc, and were separated into exercise and sedentary groups for 42 days. Differences were assessed using the general linear model (GLM) and the student’s unpaired t test with repeated measures. One protein was up regulated with 5 ppm zinc. One protein was down regulated during exercise. One protein spot was decreased in the affected LAD kidney lipid rafts. In summary, these results will further our understanding of the LAD mutation and the role of exercise in altering zinc homeostasis.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subject16-BAC
dc.subjectBull Terrier
dc.subjectExercise
dc.subjectKidney
dc.subjectLethal Acrodermatitis
dc.subjectLiver
dc.subjectZinc
dc.subjectZinc Deficiency
dc.titleZinc deficiency and exercise
dc.title.alternativeeffects on the protein composition of lipid rafts
dc.typeThesis
dc.description.degreeMS
dc.description.departmentFoods and Nutrition
dc.description.majorFoods and Nutrition
dc.description.advisorArthur Grider
dc.description.committeeArthur Grider
dc.description.committeeJames Hargrove
dc.description.committeeJoan Fischer


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