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dc.contributor.authorHenriksen, James Ralph
dc.date.accessioned2014-03-04T03:26:01Z
dc.date.available2014-03-04T03:26:01Z
dc.date.issued2008-08
dc.identifier.otherhenriksen_james_r_200808_phd
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/henriksen_james_r_200808_phd
dc.identifier.urihttp://hdl.handle.net/10724/24916
dc.description.abstractDimethylsulfoniopropionate (DMSP) is a ubiquitous marine compound whose degradation is important in carbon and sulfur cycles and influences global climate due to its degradation product dimethyl sulfide (DMS). Silicibacter pomeroyi, a member of the a marine Roseobacter clade, is a model system for the study of DMSP degradation. S. pomeroyi can cleave DMSP to DMS and carry out demethylation to methanethiol (MeSH), as well as degrade both these compounds. Differential display proteomics was used to find proteins whose abundance increased when chemostat cultures of S. pomeroyi were grown with DMSP as the sole carbon source. Bioinformatic analysis of these genes and their gene clusters suggested roles in DMSP metabolism. A genetic system was developed for S. pomeroyi that enabled gene knockout to confirm the function of these genes.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subjectSilicibacter pomeroyi
dc.subjectRuegeria pomeroyi
dc.subjectdimethylsulfoniopropionate
dc.subjectDMSP
dc.subjectroseobacter
dc.subjectdimethyl sulfide
dc.subjectDMS
dc.subjectmethanethiol
dc.subjectMeSH
dc.subjectmarine
dc.subjectenvironmental isolate
dc.subjectproteomics
dc.subjectgenetic system
dc.subjectphysiology
dc.subjectmetabolism
dc.titlePhysiology of dimethylsulfoniopropionate metabolism in a model marine Roseobacter, Silicibacter pomeroyi
dc.typeDissertation
dc.description.degreePhD
dc.description.departmentMicrobiology
dc.description.majorMicrobiology
dc.description.advisorWilliam B. Whitman
dc.description.committeeWilliam B. Whitman
dc.description.committeeAnne O. Summers
dc.description.committeeJoy B. Doran Peterson
dc.description.committeeSamantha B. (Mandy) Joye
dc.description.committeeMary Ann Moran


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