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dc.contributor.authorKulkarni, Kaumudi
dc.date.accessioned2014-03-04T03:21:13Z
dc.date.available2014-03-04T03:21:13Z
dc.date.issued2008-05
dc.identifier.otherkulkarni_kaumudi_a_200805_ms
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/kulkarni_kaumudi_a_200805_ms
dc.identifier.urihttp://hdl.handle.net/10724/24668
dc.description.abstractSeptins are novel cytoskeletal proteins found in animals, fungi and microsporidia. They are essential for orderly cell division and are major determinants of morphology. The model filamentous fungus Aspergillus nidulans has five septins: AspA, AspB, AspC, AspD and AspE. In vivo localization of the AspD-GFP fusion protein shows that aspD localizes to dormant conidia, isotropically growing conidia, germ tubes, hyphal tips, septa, along the hyphae, at the base of branches, at the periphery of branches, and at metulae and phialides in conidiophores. Deletion of the aspD gene resulted in early germination of conidia, multiple germ tubes emergence, hyperbranching, early septation, swollen conidia, hyphal splits and abnormal conidiophores. From this we suggest that aspD in A. nidulans influences germination timing, germ tube emergence, conidial and basal compartment morphology, hyphal tip integrity, septum formation timing and branch emergence. Overall, AspD is thought to be involved in new growth emergence in the vegetative phase of A. nidulans.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subjectAspergillus nidulans
dc.subjectseptins
dc.subjectAspD
dc.subjectgerm tubes
dc.subjectsepta
dc.subjecthyphal splits
dc.titleAspergillus nidulans septin AspD appears to regulate new growth emergence in the vegetative phase
dc.typeThesis
dc.description.degreeMS
dc.description.departmentPlant Biology
dc.description.majorPlant Biology
dc.description.advisorMichelle Momany
dc.description.committeeMichelle Momany
dc.description.committeeZheng-Hua Ye
dc.description.committeeSarah Covert


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