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dc.contributor.authorAvila, Andres Rodriguez
dc.date.accessioned2014-03-04T02:49:29Z
dc.date.available2014-03-04T02:49:29Z
dc.date.issued2007-12
dc.identifier.otherrodriguez_andres_200712_ms
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/rodriguez_andres_200712_ms
dc.identifier.urihttp://hdl.handle.net/10724/24352
dc.description.abstractInfectious laringotracheitis virus (ILTV) is associated with serious economic losses due to clinical signs, mortality, decreased egg production, and predisposition to other avian pathogens. The virus is a member of family herpesviridae, subfamily Alphaherpesvirinae, and it is taxonomically classified as Gallid herpesvirus 1. Although it was the first poultry pathogen controlled by vaccination, ILTV is still a major problem in areas where dense bird populations exist. Currently, there are two main types of ILTV live vaccines commercially available, those attenuated by sequential passages in chicken embryos (CEO) or by sequential passages in tissue culture (TCO). The replication, transmission, and protection of the CEO and TCO vaccines were evaluated using vaccinated, contact-exposed, and sentinel specific pathogen free chickens. No differences were observed in the ability of the CEO and TCO vaccines to replicate in the upper respiratory tract, to transmit to contact-exposed birds, and to induce protection against the challenge virus. However, chickens contact-exposed to vaccinates were not protected against challenge.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subjectInfectious laringotracheitis virus
dc.subjectILTV
dc.subjectILT
dc.subjectchicken embryo origin vaccine-CEO
dc.subjecttissue culture origin vaccine-TCO
dc.subjectreal time polymerase chain reaction
dc.subjectgenome copy number
dc.subjectvirus isolation replication
dc.subjecttransmission
dc.subjectprotection.
dc.titleReplication, transmission, and protection of live-attenuated infectious laryngotracheitis virus (ILTV) vaccines
dc.typeThesis
dc.description.degreeMS
dc.description.departmentInfectious Diseases
dc.description.majorInfectious Diseases
dc.description.advisorMaricarmen García
dc.description.committeeMaricarmen García
dc.description.committeeCharles Hofacre
dc.description.committeeJohn Glisson


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