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dc.contributor.authorOnyenwoke, Rob Uche
dc.date.accessioned2014-03-04T02:28:38Z
dc.date.available2014-03-04T02:28:38Z
dc.date.issued2006-12
dc.identifier.otheronyenwoke_rob_u_200612_phd
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/onyenwoke_rob_u_200612_phd
dc.identifier.urihttp://hdl.handle.net/10724/23703
dc.description.abstractThis dissertation represents a diversified study of the biochemical, physiological, and genetic traits of members of the low G+C subdivision of the Gram-type positive bacteria, also known as the'Firmicutes'. The phylum 'Firmicutes' contains a diverse array of taxa that are not easily separated into coherent phylogenetic groups by any one physiological trait, such as endospore-formation or dissimilatory iron reduction. This dissertation considers numerous contemporary, and highly convergent in providing breadth and scope of the subject matter, methods of study. The principle aim was to examine the lineage'Firmicutes' by a) a genomic study of the occurrence or absence of endosporulation genes in numerous members of the lineage, b) classic biochemical studies of the enzymes responsible for biotic iron reduction, and c) culture-dependent studies and isolations of various'Firmicutes' to both identify new iron-reducers and better resolve the taxonomy of the lineage. The work with endosporulation genes has shown there might not be a distinct set of "endosporulation-specific" genes. This raises several new questions about this exceptionally complex process. The work described here on "ferric reductases" suggests there are enzymes capable of iron reduction that also have additional activities. The isolation of novel bacteria presented here have added to the diversity of the'Firmicutes' but have also added to the phylogenetic and taxonomic complexity of this group. Traditional boundaries for families and genera have been weakened or shown to be in need of further studies.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subjectGram-type positive bacteria
dc.subjectFirmicutes
dc.subjectThermophiles
dc.subjectEndospores
dc.subjectDissimilatory iron reduction
dc.subjectQuinones
dc.subjectOxidative stress
dc.subjectThe University of Georgia
dc.titleThe physiology of the Firmicutes
dc.title.alternativenovel dissimilatory iron-reducing bacteria, oxidoreductase enzymes, and the endosporulating bacteria
dc.typeDissertation
dc.description.degreePhD
dc.description.departmentMicrobiology
dc.description.majorMicrobiology
dc.description.advisorJuergen Wiegel
dc.description.committeeJuergen Wiegel
dc.description.committeeWilliam B. Whitman
dc.description.committeeRobert J. Maier
dc.description.committeeHarry A. Dailey
dc.description.committeeMichael W. W. Adams


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