Show simple item record

dc.contributor.authorGregg, Shonetta Delaine
dc.date.accessioned2014-03-04T02:26:55Z
dc.date.available2014-03-04T02:26:55Z
dc.date.issued2006-12
dc.identifier.othergregg_shonetta_d_200612_phd
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/gregg_shonetta_d_200612_phd
dc.identifier.urihttp://hdl.handle.net/10724/23631
dc.description.abstractJet propellant 8 (JP-8) is a complex mix of hydrocarbons used by NATO (North Atlantic Treaty Organization) countries in military aircrafts and vehicles. The exposure of civilians as well as servicemen is of great importance. JP-8 contains many components that have shown to be related to many ill effects including: benzene (leukemia), naphthalene (cataract, laryngeal carcinoma, neoplasms), and long chain hydrocarbons have been shown to increase the carcinogenicity of other compounds present in JP-8 related to the incidence of lung cancer). The analysis of this fuel is a very arduous task because its composition varies from batch to batch and contains thousands of components. Therefore accurate identification of the compounds present in this fuel along with an accurate, sensitive and precise analytical method are needed to improve the efforts to develop a PB/PK model for this fuel. A PB/PK model will be effective in describing and predicting plasma and tissue concentrations of JP-8 and many of its components in rodents and humans. Chapter 1 reviews methods currently in the literature for the analysis of JP-8 hydrocarbons and petroleum. The identification of compounds present in JP-8, including the best sampling methods for the three phases of JP-8 are presented in Chapter 2. The validation of an analytical method for a representative mix of JP-8 in blood and liver matrices is included in Chapter 3.
dc.languageeng
dc.publisheruga
dc.rightspublic
dc.subjectJet propellant 8
dc.subjectJP-8
dc.subjecthydrocarbon
dc.subjectpetroleum
dc.subjectVolatile organic hydrocarbons
dc.subjectVOC
dc.subjectPolyaromatic hydrocarbons
dc.subjectPAH
dc.subjectMass spectrometry
dc.subjectGas Chromatography
dc.subjectSolid phase Microextraction
dc.subjectGC/MS
dc.subjectSPME
dc.subjection trap
dc.subjectBTEX
dc.titleAnalytical methods for the determination and characterization of jet propellant 8 (JP-8)
dc.typeDissertation
dc.description.degreePhD
dc.description.departmentPharmaceutical and Biomedical Sciences
dc.description.majorPharmacy
dc.description.advisorMichael Bartlett
dc.description.committeeMichael Bartlett
dc.description.committeeJeffrey Fisher
dc.description.committeeWarren Beach
dc.description.committeeJonathan Amster
dc.description.committeeAnthony Capomacchia


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record