Normal aging associated functional alternations in auditory sensory and working memory processing
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The purpose of the present study was to determine normal aging associated changes in brain functions during auditory sensory and auditory working memory processing by magneto-encephalography (MEG) measurement. Old and young participants were recruited from data recording. It is found that though there are no significant age associated differences in behavioral performance; normal aging associated brain activations differ between age groups. For brain activations in auditory sensory processing, though both age groups activate the same cortical regions and show a habituation pattern on stimulus rate effects, old participants have larger response magnitude and faster response speed than young participants. For brain activations in auditory working memory, old participants brain responses are slower than young participants and different cortical areas of two age groups are activated in the same experiment task. The possible underlying mechanisms of these normal aging associated brain responses differences are discussed further.