Dating and analysis of whole genome duplications in Arabidopsis and rice
Chapman, Brad Alan
MetadataShow full item record
Whole genome duplication events have influenced the evolutionary history of many eukaryotic organisms. Subsequent diploidization processes result in the retention of a subset of duplicated genes and rearrange the genome through recombination and deletion. As a result of these genome-wide changes, characterization of ancient duplications and the evolutionary factors that result in duplicate retention has been a major challenge. This research presents a new phylogenetic approach for dating whole genome duplications that incorporates evolutionary history. Using this approach, ancient duplication events in Arabidopsis thaliana and Oryza sativa (rice) were characterized. Retained duplicated and singleton genes from these events were analyzed to determine the unique features leading to duplicate retention. In contrast to traditional theories about duplicate gene evolution, duplicated genes were found to be more conservative in their recent evolution than singletons, perhaps due to a need for preservation of critical functionality. This has important consequences for considering the role of duplication in the evolution of genomic complexity.