Effects of four weeks of increased physical activity on individuals with chronic fatigue syndrome
Black, Christopher Durham
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Chronic fatigue syndrome (CFS) is associated with reduced activity levels. Physiological differences between CFS and sedentary healthy subjects at baseline and increased activity levels were examined. No differences between groups were seen for blood flow, strength, or overall mood. Oxygen delivery was slightly impaired. Large group differences were seen in self-reported fatigue and muscle pain. Both groups increased activity levels 25-30% over 4 weeks. No training effects on blood flow, strength, or oxygen delivery were seen in either group. Controls showed an increase in overall mood with training, while CFS subjects reported no benefit of training on mood, fatigue, or muscle pain. In conclusion, CFS subjects had large differences in mood, pain, and fatigue compared to controls. Small differences in blood flow, strength, and oxygen delivery were observed. Increasing activity in CFS patients did not improve physiological or psychological measurements, suggesting that reduced activity can’t explain abnormalities associated with CFS.