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dc.contributor.authorEsposito, Tina
dc.date.accessioned2014-03-03T20:08:23Z
dc.date.available2014-03-03T20:08:23Z
dc.date.issued2002-05
dc.identifier.otheresposito_tina_m_200205_ms
dc.identifier.urihttp://purl.galileo.usg.edu/uga_etd/esposito_tina_m_200205_ms
dc.identifier.urihttp://hdl.handle.net/10724/20539
dc.description.abstractPlacental abnormalities are proving to be a formidable obstacle to overcome in the nuclear transfer process. In the bovine, it is the trophoblast cells which make the major contribution to the parenchyma cells of the placenta. Previous studies have shown trophoblast cells to be feeder layer dependent, and, in the mouse, fibroblast growth factor-4 dependent, to remain undifferentiated and in a proliferating state. To date, t here have been no reports o f a bovine trophoblast cell line that is not feeder layer dependent, nor are there any studies determining the effects of fibroblast growth factor-4 on bovine trophoblast. It would be useful to have a stable line of bovine trophoblast cells, for in vitro studies, to determine if these cells are capable o f contributing the trophectoderm lineage in vitro, and eventually in vivo, t o aid in development of a normal, functioning placenta.
dc.publisheruga
dc.rightspublic
dc.subjectPlacenta
dc.subjectBovine
dc.subjectTrophoblast
dc.subjectFibroblast growth factor-4
dc.subjectNuclear transfer
dc.subjectFeeder layers
dc.titlePlacentation in the bovine with specific emphasis on the role of the trophoblast cells and placental abnormalities associated with the nuclear transfer process
dc.typeThesis
dc.description.degreeMS
dc.description.departmentAnimal and Dairy Science
dc.description.majorAnimal and Dairy Science
dc.description.advisorSteve Stice
dc.description.committeeSteve Stice
dc.description.committeeBenjamin Brackett
dc.description.committeeGeorge Rampacek


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