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dc.contributor.authorMao, Fenglou
dc.contributor.authorWilliams, David
dc.contributor.authorZhaxybayeva, Olga
dc.contributor.authorPoptsova, Maria
dc.contributor.authorLapierre, Pascal
dc.contributor.authorGogarten, J P
dc.contributor.authorXu, Ying
dc.date.accessioned2013-06-12T14:52:42Z
dc.date.available2013-06-12T14:52:42Z
dc.date.issued2012-06-07
dc.identifier.citationBMC Bioinformatics. 2012 Jun 07;13(1):123
dc.identifier.urihttp://dx.doi.org/10.1186/1471-2105-13-123
dc.identifier.urihttp://hdl.handle.net/10724/19587
dc.description.abstractAbstractBackgroundThe frequent exchange of genetic material among prokaryotes means that extracting a majority or plurality phylogenetic signal from many gene families, and the identification of gene families that are in significant conflict with the plurality signal is a frequent task in comparative genomics, and especially in phylogenomic analyses. Decomposition of gene trees into embedded quartets (unrooted trees each with four taxa) is a convenient and statistically powerful technique to address this challenging problem. This approach was shown to be useful in several studies of completely sequenced microbial genomes.ResultsWe present here a web server that takes a collection of gene phylogenies, decomposes them into quartets, generates a Quartet Spectrum, and draws a split network. Users are also provided with various data download options for further analyses. Each gene phylogeny is to be represented by an assessment of phylogenetic information content, such as sets of trees reconstructed from bootstrap replicates or sampled from a posterior distribution. The Quartet Decomposition server is accessible at http://quartets.uga.edu.ConclusionsThe Quartet Decomposition server presented here provides a convenient means to perform Quartet Decomposition analyses and will empower users to find statistically supported phylogenetic conflicts.
dc.titleQuartet decomposition server: a platform for analyzing phylogenetic trees
dc.typeJournal Article
dc.date.updated2013-06-07T13:43:05Z
dc.description.versionPeer Reviewed
dc.language.rfc3066en
dc.rights.holderFenglou Mao et al.; licensee BioMed Central Ltd.


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