Now showing items 1-10 of 69
Advancing Data Reuse in Phyloinformatics Using an Ontology-Driven Semantic Web Approach
Abstract Phylogenetic analyses can resolve historical relationships among genes, organisms or higher taxa. Understanding such relationships can elucidate a wide range of biological phenomena, ...
Open questions: genomics and how far we haven¿t come
Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer
Abstract Background Reciprocal interactions between lung mesenchymal and epithelial cells play essential roles in lung organogenesis and homeostasis. Although the molecular markers and related ...
Identifying accelerometer nonwear and wear time in older adults
Abstract Background Five accelerometer-derived methods of identifying nonwear and wear time were compared with a self-report criterion in adults ≥ 56 years of ...
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery
Abstract Background The small ruminant parasite Haemonchus contortus is the most widely used parasitic nematode in drug discovery, vaccine development and anthelmintic resistance research. Its remarkable propensity to ...
Mapping out the structural changes of natural and pretreated plant cell wall surfaces by atomic force microscopy single molecular recognition imaging
Abstract Background Enzymatic hydrolysis of lignocellulosic biomass (mainly plant cell walls) is a critical process for biofuel production. This process is greatly hindered by the natural complexity ...
Respiratory symptoms and lung function 8¿10 months after community exposure to chlorine gas: a public health intervention and cross-sectional analysis
Abstract Background We implemented a community based interventional health screening for individuals located within one mile of a 54 metric tons release of liquid chlorine following a 16 tanker ...
No-boundary thinking in bioinformatics research
Abstract Currently there are definitions from many agencies and research societies defining “bioinformatics” as deriving knowledge from computational analysis of large volumes of biological and biomedical ...
Reduced cerebral blood flow and white matter hyperintensities predict poor sleep in heart failure
Abstract Background Poor sleep is common in heart failure (HF), though mechanisms of sleep difficulties are not well understood. Adverse brain changes among regions important for sleep have been ...
Selection and validation of reference genes for gene expression analysis in apomictic and sexual Cenchrus ciliaris
Abstract Background Apomixis is a naturally occurring asexual mode of seed reproduction resulting in offspring genetically identical to the maternal plant. Identifying differential gene expression ...