Now showing items 1-4 of 4
Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats
Abstract Background Minocycline, a semi-synthetic tetracycline antibiotic, is an effective neuroprotective agent in animal models ...
Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke
Abstract Background Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) are increased in the brain after experimental ischemic stroke in rats. These two proteases are involved with the ...
Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model of type 2 diabetes
Abstract Background Interruption of flow through of cerebral blood vessels results in acute ischemic stroke. Subsequent breakdown ...
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke
Abstract Background While gelatinase (MMP-2 and -9) activity is increased after focal ischemia/reperfusion injury in the brain, the ...