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Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms

Yang, Jack Y; Dunker, A K; Liu, Jun S; Qin, Xiang; Arabnia, Hamid R; Yang, William; Niemierko, Andrzej; Chen, Zhongxue; Luo, Zuojie; Wang, Liangjiang; Liu, Yunlong; Xu, Dong; Deng, Youping; Tong, Weida; Yang, Mary Q (2014-12-16)

Abstract Advances of high-throughput technologies have rapidly produced more and more data from DNAs and RNAs to proteins, especially large volumes of genome-scale data. However, connection of the genomic information to ...

Identification of genes and pathways involved in kidney renal clear cell carcinoma

Yang, William; Yoshigoe, Kenji; Qin, Xiang; Liu, Jun S; Yang, Jack Y; Niemierko, Andrzej; Deng, Youping; Liu, Yunlong; Dunker, A K; Chen, Zhongxue; Wang, Liangjiang; Xu, Dong; Arabnia, Hamid R; Tong, Weida; Yang, Mary Q (2014-12-16)

Abstract Background Kidney Renal Clear Cell Carcinoma (KIRC) is one of fatal genitourinary diseases and accounts for most malignant kidney tumours. KIRC has been shown resistance to radiotherapy and chemotherapy. Like many ...