Now showing items 1-4 of 4

    • Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms 

      Yang, Jack Y; Dunker, A K; Liu, Jun S; Qin, Xiang; Arabnia, Hamid R; Yang, William; Niemierko, Andrzej; Chen, Zhongxue; Luo, Zuojie; Wang, Liangjiang; Liu, Yunlong; Xu, Dong; Deng, Youping; Tong, Weida; Yang, Mary Q (2014-12-16)
      Abstract Advances of high-throughput technologies have rapidly produced more and more data from DNAs and RNAs to proteins, especially large volumes of genome-scale data. However, connection of the genomic information to ...
    • Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species 

      Bradnam, Keith R; Fass, Joseph N; Alexandrov, Anton; Baranay, Paul; Bechner, Michael; Birol, Inanç; Boisvert, Sébastien; Chapman, Jarrod A; Chapuis, Guillaume; Chikhi, Rayan; Chitsaz, Hamidreza; Chou, Wen-Chi; Corbeil, Jacques; Del Fabbro, Cristian; Docking, T R; Durbin, Richard; Earl, Dent; Emrich, Scott; Fedotov, Pavel; Fonseca, Nuno A; Ganapathy, Ganeshkumar; Gibbs, Richard A; Gnerre, Sante; Godzaridis, Élénie; Goldstein, Steve; Haimel, Matthias; Hall, Giles; Haussler, David; Hiatt, Joseph B; Ho, Isaac Y; Howard, Jason; Hunt, Martin; Jackman, Shaun D; Jaffe, David B; Jarvis, Erich D; Jiang, Huaiyang; Kazakov, Sergey; Kersey, Paul J; Kitzman, Jacob O; Knight, James R; Koren, Sergey; Lam, Tak-Wah; Lavenier, Dominique; Laviolette, François; Li, Yingrui; Li, Zhenyu; Liu, Binghang; Liu, Yue; Luo, Ruibang; MacCallum, Iain; MacManes, Matthew D; Maillet, Nicolas; Melnikov, Sergey; Naquin, Delphine; Ning, Zemin; Otto, Thomas D; Paten, Benedict; Paulo, Octávio S; Phillippy, Adam M; Pina-Martins, Francisco; Place, Michael; Przybylski, Dariusz; Qin, Xiang; Qu, Carson; Ribeiro, Filipe J; Richards, Stephen; Rokhsar, Daniel S; Ruby, J G; Scalabrin, Simone; Schatz, Michael C; Schwartz, David C; Sergushichev, Alexey; Sharpe, Ted; Shaw, Timothy I; Shendure, Jay; Shi, Yujian; Simpson, Jared T; Song, Henry; Tsarev, Fedor; Vezzi, Francesco; Vicedomini, Riccardo; Vieira, Bruno M; Wang, Jun; Worley, Kim C; Yin, Shuangye; Yiu, Siu-Ming; Yuan, Jianying; Zhang, Guojie; Zhang, Hao; Zhou, Shiguo; Korf, Ian F (2013-07-22)
      Abstract Background The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished genome ...
    • Identification of genes and pathways involved in kidney renal clear cell carcinoma 

      Yang, William; Yoshigoe, Kenji; Qin, Xiang; Liu, Jun S; Yang, Jack Y; Niemierko, Andrzej; Deng, Youping; Liu, Yunlong; Dunker, A K; Chen, Zhongxue; Wang, Liangjiang; Xu, Dong; Arabnia, Hamid R; Tong, Weida; Yang, Mary Q (2014-12-16)
      Abstract Background Kidney Renal Clear Cell Carcinoma (KIRC) is one of fatal genitourinary diseases and accounts for most malignant kidney tumours. KIRC has been shown resistance to radiotherapy and chemotherapy. Like many ...
    • The emerging genomics and systems biology research lead to systems genomics studies 

      Yang, Mary Q; Yoshigoe, Kenji; Yang, William; Tong, Weida; Qin, Xiang; Dunker, A K; Chen, Zhongxue; Arbania, Hamid R; Liu, Jun S; Niemierko, Andrzej; Yang, Jack Y (2014-12-16)
      Abstract Synergistically integrating multi-layer genomic data at systems level not only can lead to deeper insights into the molecular mechanisms related to disease initiation and progression, but ...